Posts Tagged‘johns hopkins university’

NASA Detects Flowing Water on Mars.

We’ve known for some time that water exists in some forms on Mars. The Viking program, which consisted of both orbiter and lander craft, showed that Mars’ surface had many characteristics that must have been shaped by water. Further probes such as Mars Odyssey and the Phoenix Lander showed that much of the present day water that Mars holds is present at the poles, trapped in the vast frozen tundra. There’s been a lot of speculation about how liquid water could exist on Mars today however no conclusive proof had been found. That was until today when NASA announced it had proof that liquid water flows on Mars, albeit in a very salty form.

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The report comes out of the Georgia Institute of Technology with collaborators from NASA’s Ames Research Center, Johns Hopkins University, University of Arizona and the Laboratoire de Planétologie et Géodynamique. Using data gathered from the Mars Reconnaissance Orbiter the researchers had identified that there were seasonal geologic features on Mars’ surface. These dark lines (pictured above) were dubbed recurring slope lineae would change over time, darkening and appearing to flow during the warmer months and then fading during the colder months. It has been thought for some time that these slopes were indicative of liquid water flows however there wasn’t any evidence to support that theory.

This is where the MRO’s Compact Reconnaissance Imaging Spectrometer for Mars (CRISM) comes into play. This instrument was specifically designed to detect water on Mars by looking at varying wavelengths of light emitted from the planet’s surface. Once the target sites were identified CRISM was then pointed at them and their surface composition analysed. What was found at the RSL sites were minerals called hydrated salts which, when mixed with water, would lower the freezing point of the water significantly. Interestingly these hydrated salts were only detected in places were the RSL features were particularly wide as other places, where the RSLs were slimmer, did not show any signs of hydrated salts.

These salts, called perchlorates, have been seen before by several other Mars missions although they’ve never been witnessed in hydrated form before. These perchlorates can potentially keep water from freezing at temperatures down to -70°C. Additionally some of these perchlorates can be used in the manufacturing of rocket fuel, something which could prove to be quite valuable for future missions to Mars. Of course they’re likely not in their readily usable form, requiring some processing on site before they can be utilized.

Data like this presents many new opportunities for further research on Mars. It’s currently postulated that these RSLs are likely the result of a shallow subsurface flow which is wicking up to the surface when the conditions are warmer. If this is the case then these sites would be the perfect place for a rover to investigate as there’s every chance it could directly sample martian water at these sites. Considering that wherever we find liquid water on Earth we find life then there’s great potential for the same thing to happen on Mars. If there isn’t then that will also tell us a lot which means its very much worth investigating.

3D Printed Prosthesis Regenerates Nerves.

Nerve damage has almost always been permanent. For younger patients there’s hope for full recovery after an incident but as we get older the ability to repair nerve damage decreases significantly. Indeed by the time we reach our 60s the best we could hope for is what’s called “protective sensation”, the ability to determine things like hot from cold. The current range of treatments are mostly limited to grafts, often using nerves from the patient’s own body to repair the damage, however even those have limited success in practice. However that could all be set to change with the development of a process which can produce nerve regeneration conduits using 3D scanning and printing.

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The process was developed by a collaboration of numerous scientists from the following institutions: University of Minnesota, Virginia Tech, University of Maryland, Princeton University, and Johns Hopkins University. The research builds upon one current cutting edge treatment which uses special structures to trigger regeneration, called nerve guidance conduits. Traditionally such conduits could only be produced in simple shapes, meaning they were only able to repair nerve damage in straight lines. This new treatment however can work on any arbitrary nerve structure and has proven to work in restoring both motor and sensory function in severed nerves both in-vitro (in a petri dish) and in-vivo (in a living thing).

How they accomplished this is really quite impressive. First they used a 3D scanner to reproduce the structure of the nerve they’re trying to regenerate, in this case it was the sciatic nerve (pictured above). Then they used the resulting model to 3D print a nerve guidance conduit that was the exact size and shape required. This was then implanted into a mouse who had a 10mm gap in their sciatic nerve (far too long to be sewn back together). This conduit then successfully triggered the regeneration of the nerve and after 10 weeks the rat showed a vastly improved ability to walk again. Since this process had only been verified on linear nerves before this process shows great promise for regenerating much more complicated nerve structures, like those found in us humans.

The great thing about this is that it can be used for any arbitrary nerve structure. Hospitals equipped with such a system would be able to scan the injury, print the appropriate nerve guide and then implant it into the patient all on site. This could have wide reaching ramifications for the treatment of nerve injuries, allowing far more to be treated and without the requisite donor nerves needing to be harvested.

Of course this treatment has not yet been tested in humans but the FDA has approved similar versions of this treatment in years past which have proven to be successful. With that in mind I’m sure that this treatment will prove successful in a human model and from there it’s only a matter of time before it finds its way into patients worldwide. Considering how slow progress has been in this area it’s quite heartening to see dramatic results like this and I’m sure further research into this area will prove just as fruitful.